The group peforms genetic analysis of unsolved patients with suspected monogenic disease as well as systematic molecular characterization of large cohorts of individuals with movement disorders and related rare diseases. The focus is on the application of diverse high-throughput methods for the analysis of genomic and supragenomic information, the investigation in laboratory models and the translation back into clinical practice. The research group investigates the genetic basis of dystonia and cerebral palsy as well as other movement disorders. There are various international collaborations and close links to numerous specialty outpatient clinics and clinical centers, in particular the ZSE TUM. Networking with patient associations (Dystonia Europe, Dystonia Medical Research Foundation) and consortia (International Cerebral Palsy Genomics Consortium) are an important part of the activities. The research work is funded by the German Research Foundation (DFG), the Else Kröner-Fresenius Foundation, the BMBF and the Institute for Advanced Study of the Technical University of Munich. Members of the group: Ivana Dzinovic (PhD program/genomics, high-throughput methods), Alice Saparov (PhD program/bioinformatics), Ugo Sorrentino (geneticist/functional studies, disease networks), Elisabetta Indelicato (neurologist/EJP-RD Research Mobility Fellowship), Lisa Koll (cand. med.), and physicians of our institute.