The Center for Rare Diseases at the Klinikum rechts der Isar of the Technical University of Munich (ZSE TUM) is a central point of contact for patients with a rare disease who are looking for the right experts for both diagnostics and treatment. Patients with unclear symptoms can present themselves for a consultation. 

The ZSE supports cooperative research projects, participates in teaching and further education and works closely with various self-help groups. 

The Institute of Human Genetics is represented by various B Centers. The A-Centre is headed by Prof. Dr. Höfele.  More information: ZSE TUM

The Bavarian Genomes project links the Centers for Rare Diseases in Bavaria and aims to identify causative sequence variants in the genome of patients with unexplained rare diseases. The determination of DNA and RNA sequences is carried out in a central laboratory at our institute using state-of-the-art genome sequencing technology. The doctors at the respective centers have controlled access and can evaluate and interpret their patients' data. The project improves the care of patients with rare diseases in Bavaria, creates crystallization points for research into new treatments and is funded by the Bavarian State Ministry of Science and the Arts.

The German Human Genome Phenome Archive (GHGA) is one of the 30 consortia of the National Research Data Infrastructure (NFDI). GHGA is building a secure national infrastructure for human omics data in order to make genome data usable for scientific research while preventing data misuse and protecting patient privacy. GHGA works closely with other research communities at national and international level, such as the European Genome-Phenome Archive (EGA) and the Global Alliance for Genomic Health (GA4GH).     

Within the German (mitoNET) and the global (GENOMIT) network for mitochondrial diseases, we have established the global patient registry and the largest biobank for mitochondrial diseases.

DigiMed Bayern is a lighthouse project and is funded by the Bavarian State Ministry of Health and Care (StMGP) as part of the BAYERN DIGITAL II master plan. The aim of Digimed is to integrate P4 medicine (predictive, preventive, personalized and participatory).

PreDYT is a European collaborative project with sites in Munich (Klinikum rechts der Isar of the Technical University of Munich - Institute of Human Genetics, PI PD Dr. Michael Zech), Milan, Paris, Zurich and Luxembourg. PreDYT investigates the genomic basis and biomarkers of rare forms of the movement disorder dystonia. 

The European Restless Legs Syndrome Study Group (EURLSSG) is an organization of professionals dedicated to the promotion of basic and clinical research on Restless Legs Syndrome (RLS). Its mission includes the cooperative planning, execution, analysis, and reporting of multicenter studies on RLS.